Condition: BRAND NEW
ISBN: 9781118622124
Year: 2018
Publisher: John Wiley & Sons (UK)
Pages: 448


Description:


An integrated presentation of the basic science and clinical applications of anticancer agents


Aimed at both undergraduate and postgraduate readers, this unique text provides readers with a fully-integrated presentation of all aspects of the science of anticancer drugs, including their chemistry, pharmacology, and clinical applications.


After heart disease, cancer is the number one killer worldwide, and the tumor microenvironment is forever changing, creating an ever-greater demand for safer, more effective anticancer agents. In response to that demand, the $100 billion cancer drug market continues to grow, with our increased understanding of cancer leading to new drugs being used clinically almost every year.


Anticancer Therapeutics is divided into three sections. Section 1 is an introduction to cancer and therapeutics, and covers the etiology and cellular and molecular basis of cancer. In Section 2, the authors focus on the anticancer agents — their discovery, synthesis, mode of action, mechanisms of resistance, and adverse reactions. Section 3 focuses on specific cancers, explaining how and why the various agents discussed in Section 2 are used, both individually and in combination, to treat different cancers.


Integrates aspects of basic science, including chemistry and pharmacology and clinical medicine in relation to cancer therapeutics



Written by an author team comprising specialists in medicinal chemistry, pharmacology, and oncology

Features full-color images throughout illustrating how drugs bind to cellular targets and exert their pharmacologi