Botanical name: Aesculus hippocastanum
Common name: Horsechestnut, Horse chestnut, European horsechestnut, Buckeye, Conker tree
Plant part: Seed
Strength: 1:2
Source (Organic or Trade): Trade
Country of Origin: Poland
Weekly Dosage (mL): 15-40mL 

Actions: Anti-inflammatory, Venous tonic

Main indication: Varicose veins/venous insufficiency, haemorrhoids, capillary fragility, bruising, restless leg syndrome

Safety information: Caution with GORD (saponins can aggravate). Do not apply directly to broken skin.

Drug Interactions: Anticoagulants & antiplatelet agents such as warfarin and aspirin - Potentiation of anticoagulant effects reported

Potential Positive drug interactions: 5-Flourouracil - In vitro potentiation of activity against hepatocellular carcinoma reported for beta-aescin

Article: ß-Aescin from Horse Chestnut potentiates 5-Fluorouracil against human hepatocellular carcinoma (2010), Horse Chestnut and venous insufficiency (1999)

Case study: Horse Chestnut and warfarin interaction (1999)